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Hepatocyte
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Human primary hepatocyte Àå±â ¹è¾ç¹èÁö
Primary hepatocyte medium
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Cellartis
Y20020
Cellartis¢ç Power¢â Primary HEP Medium
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Human primary hepatocyte Àü¿ë¹èÁö
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Power¢â Primary HEP Medium 250 ml
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±×¸² 1. Àå±â ¹è¾çÇÑ human primary hepatocyte¿¡¼ ATP º¯È
°¢±â ´Ù¸¥ donor¿¡¼ À¯·¡µÈ 6Á¾ÀÇ ¼¼Æ÷¸¦ Power¢â Primary HEP Medium¿¡¼ 28ÀÏ°£ ¹è¾çÇÑ °á°ú, ¹è¾ç ±â°£ Áß human primary hepatocyteÀÇ ATP»ý»êÀÌ ¹è¾ç Ãʱâ¿Í µ¿µîÀÌ»óÀ¸·Î À¯ÁöµÇ´Â °ÍÀ» È®ÀÎÇÏ¿´´Ù.
±×¸² 2. ¹è¾ç 28ÀÏ° human primary hepatocyteÀÇ Çö¹Ì°æ À̹ÌÁö
A. °¢±â ´Ù¸¥ donor¿¡¼ À¯·¡µÈ 3Á¾ÀÇ ¼¼Æ÷¸¦ Power¢â Primary HEP Medium¿¡¼ 28ÀÏ°£ ¹è¾çÇÏ¿´´Ù. ¼¼Æ÷ÀÇ ¾çÈ£ÇÑ »óŸ¦ È®ÀÎÇÒ ¼ö ÀÖ¾ú´Ù. B. Ÿ Á¦Á¶»çÀÇ human primary hepatocyte ¹è¾ç¹èÁö medium B, medium T, medium LÀ» »ç¿ëÇÏ¿© 28ÀÏ°£ ¹è¾çÇÏ¿´À» ¶§ °£¼¼Æ÷ÀÇ »ç¸ê°ú Å»ºÐÈ°¡ °üÂûµÇ¾ú´Ù.
±×¸² 3. Àå±â ¹è¾çÇÑ human primary hepatocyteÀÇ CYP È°¼º º¯È
°¢±â ´Ù¸¥ donor¿¡¼ À¯·¡µÈ 4Á¾ÀÇ ¼¼Æ÷¸¦ Power¢â Primary HEP Medium¿¡¼ 28ÀÏ°£ ¹è¾çÇÑ °á°ú ¹è¾ç±â°£ µ¿¾È ÀÏÁ¤ÇÑ °ª ÀÌ»óÀÇ CYPÈ°¼ºÀ» À¯ÁöÇÏ´Â °ÍÀ» È®ÀÎÇÏ¿´´Ù.
±×¸² 4. 28ÀÏ°£ Àå±â ¹è¾çÇÑ human primary hepatocyteÀÇ CYP induction °á°ú
°¢±â ´Ù¸¥ donor¿¡¼ À¯·¡µÈ 4Á¾ÀÇ ¼¼Æ÷¸¦ Power¢â Primary HEP Medium¿¡¼ 26ÀÏ°£ ¹è¾çÇÏ¿´´Ù. 4Á¾ÀÇ CYP(1A2, 2B6, 3A4, 2C9) À¯µµÁ¦
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1A2 - Ome : omeprazole / 2B6 - PB : phenobarbital / 3A4 - Rif : rifampicin / 2C9 - PB : phenobarbital
Keyword :
Hepatocyte
[Àû¿ë] hiPS-HEP cells for disease modeling
[Àû¿ë] hiPS-HEP cells for drug metabolism studies
Human primary hepatocyte Àå±â ¹è¾ç¹èÁö
Primary hepatocyte medium
°£¼¼Æ÷ ºÐÈ À¯µµ ½Ã½ºÅÛ
iPS Cell to Hepatocyte Differentiation System