¿¬±¸¿ë Viral Vector »ý»ê ¼ºñ½º

À¯ÀüÀÚ Ä¡·áÁ¦ÀÇ Ãʱ⠰³¹ßÀ» Áö¿øÇϰí, ÀÓ»ó µî±Þ(clinical grade) »ý»êÀ¸·ÎÀÇ ¿øÈ°ÇÑ ÀüȯÀÌ °¡´ÉÇϵµ·Ï, ¿¬±¸(research grade)/ÀüÀÓ»ó µî±Þ(preclinical grade) ¹ÙÀÌ·¯½º »ý»ê ¼ºñ½º¸¦ Á¦°øÇÕ´Ï´Ù.
- Lentivirus
- Adeno-associated virus (AAV)
- Retrovirus
Lentivirus
´ç»çÀÇ ¿¬±¸¿ë lentivirus »ý»ê ¼ºñ½º´Â Takara BioÀÇ µ¶ÀÚÀûÀÎ transient lentiviral vector production systemÀ» »ç¿ëÇÕ´Ï´Ù. ÃÊ¿ø½ÉºÐ¸®¸¦ ÀÌ¿ëÇÑ large scale Á¤Á¦ ¼ºñ½ºµµ Á¦°øÇÕ´Ï´Ù.
Expression plasmid vector options |
Promoter |
|
Control vector |
|
Antibiotic resistance |
- Neomycin
- Hygromycin
- Puromycin
|
Virus envelope |
VSV-G pseudotype |
Adeno-associated virus
- AAVpro Helper Free SystemÀ» Àû¿ëÇÑ ´õ¿í ¾ÈÀüÇϰí helper-independent AAV vector
- Takara BioÀÇ µ¶ÀÚÀûÀÎ ÃßÃâ¹ýÀ¸·Î °íµµ·Î Á¤Á¦µÈ AAV vector
- ¸ñÀû¿¡ ¸Â´Â ´Ù¾çÇÑ Á¤Á¦ ¹æ¹ý ¼±Åà °¡´É
- ÇâÈÄ »ó¾÷ »ý»êÀ» À§ÇÑ ±Ô¸ð È®Àå °³¹ß °¡´É
Expression plasmid vector options |
Serotype |
- AAV1
- AAV2
- AAV5
- AAV6
- Customer-supplied rep-cap plasmid (pRC)
|
Promoter |
|
Control vector |
- Beta-galactosidase
- ZsGreen1
|
Retrovirus
´ç»çÀÇ ¿¬±¸¿ë retrovirus »ý»ê ¼ºñ½º´Â °í°´ÀÌ ¿øÇÏ´Â ¹ßÇö À¯Çü¿¡ µû¶ó ´Ù¾çÇÑ ¹ßÇö plasmid vectorÁß¿¡¼ ¼±ÅÃÇÒ ¼ö ÀÖ½À´Ï´Ù. Stable cell line Á¦ÀÛ°ú iPC cell line Á¦ÀÛµµ °¡´ÉÇÕ´Ï´Ù.
Expression plasmid vector options |
Expression type |
- High titer (pDON-AI-2)
- High expression (pMEI-5)
- Balanced (pDON-5)
|
Control vector |
|
Virus envelope |
|
¼ºñ½º ÇÁ·Î¼¼½º µî ÀÚ¼¼ÇÑ ¹®ÀÇ´Â ¿ÞÂÊ ¹®ÀÇ formÀ» ÀÌ¿ëÇϰųª,
oem@takara.co.kr·Î ¸ÞÀÏÀ» º¸³»ÁÖ¼¼¿ä.