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Custom Service


CMO ¼­ºñ½º ¹®ÀÇ
¿¬±¸¿ë Viral Vector »ý»ê ¼­ºñ½º


À¯ÀüÀÚ Ä¡·áÁ¦ÀÇ Ãʱ⠰³¹ßÀ» Áö¿øÇϰí, ÀÓ»ó µî±Þ(clinical grade) »ý»êÀ¸·ÎÀÇ ¿øÈ°ÇÑ ÀüȯÀÌ °¡´ÉÇϵµ·Ï, ¿¬±¸(research grade)/ÀüÀÓ»ó µî±Þ(preclinical grade) ¹ÙÀÌ·¯½º »ý»ê ¼­ºñ½º¸¦ Á¦°øÇÕ´Ï´Ù.
  • Lentivirus
  • Adeno-associated virus (AAV)
  • Retrovirus

Lentivirus
´ç»çÀÇ ¿¬±¸¿ë lentivirus »ý»ê ¼­ºñ½º´Â Takara BioÀÇ µ¶ÀÚÀûÀÎ transient lentiviral vector production systemÀ» »ç¿ëÇÕ´Ï´Ù. ÃÊ¿ø½ÉºÐ¸®¸¦ ÀÌ¿ëÇÑ large scale Á¤Á¦ ¼­ºñ½ºµµ Á¦°øÇÕ´Ï´Ù.

Expression plasmid vector options

Promoter

  • CMV
  • EF1¥á

Control vector

  • Not available

Antibiotic resistance

  • Neomycin
  • Hygromycin
  • Puromycin

Virus envelope

VSV-G pseudotype


Adeno-associated virus
  • AAVpro Helper Free SystemÀ» Àû¿ëÇÑ ´õ¿í ¾ÈÀüÇϰí helper-independent AAV vector
  • Takara BioÀÇ µ¶ÀÚÀûÀÎ ÃßÃâ¹ýÀ¸·Î °íµµ·Î Á¤Á¦µÈ AAV vector
  • ¸ñÀû¿¡ ¸Â´Â ´Ù¾çÇÑ Á¤Á¦ ¹æ¹ý ¼±Åà °¡´É
  • ÇâÈÄ »ó¾÷ »ý»êÀ» À§ÇÑ ±Ô¸ð È®Àå °³¹ß °¡´É

Expression plasmid vector options

Serotype

  • AAV1
  • AAV2
  • AAV5
  • AAV6
  • Customer-supplied rep-cap plasmid (pRC)

Promoter

  • CMV

Control vector

  • Beta-galactosidase
  • ZsGreen1

Retrovirus
´ç»çÀÇ ¿¬±¸¿ë retrovirus »ý»ê ¼­ºñ½º´Â °í°´ÀÌ ¿øÇÏ´Â ¹ßÇö À¯Çü¿¡ µû¶ó ´Ù¾çÇÑ ¹ßÇö plasmid vectorÁß¿¡¼­ ¼±ÅÃÇÒ ¼ö ÀÖ½À´Ï´Ù. Stable cell line Á¦ÀÛ°ú iPC cell line Á¦ÀÛµµ °¡´ÉÇÕ´Ï´Ù.

Expression plasmid vector options

Expression type

  • High titer (pDON-AI-2)
  • High expression (pMEI-5)
  • Balanced (pDON-5)

Control vector

  • Not available

Virus envelope

  • Amphotropic or ecotropic

¼­ºñ½º ÇÁ·Î¼¼½º µî ÀÚ¼¼ÇÑ ¹®ÀÇ´Â ¿ÞÂÊ ¹®ÀÇ formÀ» ÀÌ¿ëÇϰųª, oem@takara.co.kr·Î ¸ÞÀÏÀ» º¸³»ÁÖ¼¼¿ä.